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The effect seen after giving intraoperative intravenous magnesium sulphate on post operative pain and analgesic consumption after major spine surgeries

The effect of intraoperative intravenous magnesium sulphate on post operative pain and analgesic consumption after major spine surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/052482
Enrollment
100
Registered
2023-05-10
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Patients will receive intravenous(i.v.) magnesium sulphate: Before induction of Anaesthesia patients will receive magnesium sulphate in dose of 20mg/kg over 15min by i.v. route and 20mg

Sponsors

Mahatma Gandhi medical College and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients fulfilling American society of Anaesthesiologists grade 1,2 Patients aged between 18 years to 65 years posted for major spine surgeries

Exclusion criteria

Exclusion criteria: Patients allergic to local anaesthetics Patients on opioids for chronic pain Patients who refused to be a part of the study Patients with impared hepatic and renal function Patients on calcium channel blockers and magnesium Patients posted for surgeries with duration greater than 5hours

Design outcomes

Primary

MeasureTime frame
The study will evaluate the effectiveness of intraoperative intravenous magnesium sulphate on post operative pain in major spine surgeries by comparing NRS scale in post operative period in study groupsTimepoint: The study will evaluate the effectiveness of intraoperative intravenous magnesium sulphate on post operative pain in major spine surgeries by comparing NRS scale in post operative period in study groups at 2hours , 4hours ,6hours,12hours,24hours after emergence from Anaesthesia.

Secondary

MeasureTime frame
To note post operative nausea vomiting and adverse effects if anyTimepoint: Post operative nausea vomiting and adverse effects will be noted at 2hors,4hours,6hours,12hours,24 hours after emergence from Anaesthesia.

Countries

India

Contacts

Public ContactDr Mangilal Deganwa

Mahatma Gandhi medical College and hospital

drsunitakhs@yahoo.com07597053927

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026