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To compare Intrathecal Dexmeditomidine 10mcg versus Fentanyl 25mcg when added with Hyperbaric 0.75% Ropivacaine 18.75mg as additive in Spinal Anaesthesia in Patients Undergoing Infraumbilical Surgeries

Comparative Study of Effects of Intrathecal Dexmeditomidine versus Fentanyl as adjuvants to Hyperbaric 0.75% Ropivacaine in Patients Undergoing Infraumbilical Surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/052458
Enrollment
90
Registered
2023-05-10
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: PCS-

Interventions

Intervention1: Ropivacaine with Dexmeditomidine: 2.5ml of Hyperbaric Ropivacaine 0.75% + 10mcg Dexmeditomidine Intervention2: Ropivacaine with Fentanyl: 2.5ml of Hyperbaric Ropivacaine 0.75% + 25mcg F

Sponsors

Multidisciplinary Research Unit Dr SNMC Jodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult Patients of either sex ,aged between 18 and 60 years who will be Undergoing for infraumbilical surgeries Patients belonging to ASA-PS class1 and class 2 Patients without any severe comorbid diseases

Exclusion criteria

Exclusion criteria: Patients having any absolute contraindications for Spinal Anaesthesia such as patient not willing, raised intracranial pressure, severe hypovolemia, bleeding diathesis,local site infection,severe cardiac , respiratory,and CNS diseases are excluded from the study Pregnant females,uncontrolled diabetes and hypertension Patients with body mass index greater than 30kg/m2 Patients shorter than 150cm

Design outcomes

Primary

MeasureTime frame
Duration of Analgesia Postoperatively-VAS (visual analogue score) VAS equal or greater than 4 or time of first Analgesia requestTimepoint: Time in minutes-0,15,30,60,90,120,150,180,210,240,270,300

Secondary

MeasureTime frame
Secondary Objectives Time of onset and duration of Sensory blockade Time of onset and duration of motor blockade Maximum Sensory blockade attained and time taken for the same Time taken for two segment Sensory regression Quality of motor blockade and time taken for maximum Motor blockade To compare the hemodynamic changes and side effects such as sedation, nausea and vomiting, shivering and respiratory depressionTimepoint: Time in minutes-0,1,5,10,20,30,40,50,60,70,80,90,120,150,180,210,240,270,300,330,360,390,420,450

Countries

India

Contacts

Public ContactDr Chunnilal

Dr. S.N.Medical Collage Jodhpur

Mdmhjodhpur@gmail.com08209516803

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026