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Comparison of 3 techniques of giving oxygen to patient before general anesthesia

Prospective randomized trial comparing preoxygenation by face-mask, NIV and HFNC using expired oxygen fraction and oxygen reserve index

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/052457
Enrollment
75
Registered
2023-05-10
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Preoxygenation by NIV: Non Invasive ventilation will be given using a Bipap machine with a tight fitting NIV mask. Bipap 10cm H2O and PEEP 5cmH20 till FeO2 is 90%. Oxygen reserve index

Sponsors

All India Institute Of Medical Sciences New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I and II Patients, Posted for elective laproscopic surgery

Exclusion criteria

Exclusion criteria: 1. Patients less than 16years and more than 65 years of age 2. ASA III and IV 3. Patients with any lung disease 4. Patients with cardiac disease 5. Obesity BMI >30 Kg/m2 6. Pregnancy 7. Anaemia Hb 8. Anticipated difficult airway

Design outcomes

Primary

MeasureTime frame
Time to preoxygenation(seconds) with Face mask, NIV and HFNC: Time from start of preoxygenation to the time when FeO2 reaches 90% and the ORI value at this time pointTimepoint: Time of start of preoxygenation Time when FeO2 reaches 90% and the ORI value at this time point

Secondary

MeasureTime frame
1. SpO2: oxygen saturation 2. NIBP: Non invasive blood pressure 3. HR: Heart RateTimepoint: SpO2, NIBP and HR will be recorded at baseline and at every minute till the end of preoxygenation

Countries

India

Contacts

Public ContactDr Puneet Khanna

All India Institute Of Medical Sciences, New Delhi

k.punit@yahoo.com9873106516

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026