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Need for post operative antibiotics in extractions of teeth with periapical pathologies

Do post-operative antibiotics prevent complications in healthy adults undergoing simple extractions: a prospective randomized control trial - ANTI

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/052440
Enrollment
100
Registered
2023-05-10
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin Health Condition 2: K045- Chronic apical periodontitis

Interventions

Intervention1: Amoxicillin/clavulanic acid: 625mg dose thrice daily for 5 day Control Intervention1: paracetamol/acetaminophen: 325mg/500mg/625 mg twice daily for 3 days Control Intervention2: acecl

Sponsors

DEPARTMENT OF ORAL AND MAXILLOFACIAL SURGERY JSS DENTAL COLLEGE AND HOSPITAL MYSURU
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients who require extraction of teeth. Patients with apical periodontitis of teeth requiring extraction of teeth secondary to dental caries or periodontitis.Patients who are systemically healthy â?? ASA I and ASA II

Exclusion criteria

Exclusion criteria: Patients who donâ??t want to participate in the study. Patients who are medically compromised and where systemic antibiotics is indicated postoperatively. Patients having acute infections of teeth such as periapical abscess. Patients with other generalized infective conditions. Patients with poor oral hygiene.

Design outcomes

Primary

MeasureTime frame
Pain Erythema of mucosa Bleeding from socket Tenderness on palpation of the extraction site Rolled or everted margins of extraction socket Signs of infections like swelling, pus discharge Alveolar osteitis Tender lymph nodes Fever TrismusTimepoint: 1 week

Secondary

MeasureTime frame
local infection control methods along with standard infection control measures reduce the need for post operative antibiotics in patients undergoing atraumatic extractions of teeth with periapical pathologiesTimepoint: 1 week

Countries

India

Contacts

Public ContactEashwari Narayanan

JSS Dental College and hospital

drsathish75@gmail.com9845310737

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026