Comparing three different methods of pain relieving techniques by measuring the total pain medicines consumed during and up to 48 hours after surgery, in an adult patients between 18-70 years undergoing spine surgery - A randomised controlled trial.

Comparing the three analgesic techniques, Ultrasound-guided Erector Spinae Plane Block (ESPB) versus Modified-Thoracolumbar Interfascial Plane Block (mTLIP) versus Conventional standard technique for Perioperative analgesia following 1-3 levels of lumbar laminectomy/discectomy- A randomised, controlled clinical Trial - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/05/052390

Enrollment

Registered

2023-05-09

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Modified Thoracolumbar Interfascial Plane Block: In the mTLIP block, the local anaesthetic drug is deposited between the longissimus and iliocostalis, it is done by placing the USG prob

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing 1-3 levels of lumbar discectomy/laminectomy 2. ASA I - III 3. Age between 18 to 70 years

Exclusion criteria

Exclusion criteria: 1. History of bleeding diathesis 2. Patients on anticoagulant treatment 3. Patients with known allergies to local anaesthetics. 4. Skin infections at the site of the block area 5. Patients who are pregnant or lactating 6. Patients with moderate to severe scoliosis or any lumbar spine anatomical abnormality 7. Difficult to visualize the sonoanatomy due to any cause. 8. Morbid obesity (BMI > 35

Design outcomes

Primary

Measure	Time frame
Cumulative opioid consumption during and upto 48hrs after surgeryTimepoint: Cumulative opioid consumption during and upto 48hrs after surgery	—

Secondary

Measure	Time frame
1. The time taken to receive the first dose of rescue analgesia 2. Postoperative pain scores at rest and movement 4. Time of oral intake 5. The hemodynamics 6. Sedation score 7. The incidence of complications 8. The time taken for the block to be performed 9. To compare the anesthetic requirement 10. The time taken to obey commands 11. The duration of anesthesia and duration of surgery. Timepoint: Intraoperative (Before block, 10mins after, 20mins after, 30mins after, 40mins after, 60mins after, 1.5hrs, 2hrs and 10 mins after extubation) Post Anesthesia Care Unit (Arrival, 15mins, 30mins, 45mins, 1hr, 1.5 hrs, discharge) Post Operative ward (Arrival, 2hrs, 4hrs, 6hrs, 12hrs, 18hrs, 24hrs)	—

Measure

Time frame

1. The time taken to receive the first dose of rescue analgesia 2. Postoperative pain scores at rest and movement 4. Time of oral intake 5. The hemodynamics 6. Sedation score 7. The incidence of complications 8. The time taken for the block to be performed 9. To compare the anesthetic requirement 10. The time taken to obey commands 11. The duration of anesthesia and duration of surgery. Timepoint: Intraoperative (Before block, 10mins after, 20mins after, 30mins after, 40mins after, 60mins after, 1.5hrs, 2hrs and 10 mins after extubation) Post Anesthesia Care Unit (Arrival, 15mins, 30mins, 45mins, 1hr, 1.5 hrs, discharge) Post Operative ward (Arrival, 2hrs, 4hrs, 6hrs, 12hrs, 18hrs, 24hrs)

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Countries

India

Contacts

Public ContactSujil Ebenezar Sam

The Tamilnadu Dr.M.G.R. Medical University

sujilebby11@gmail.com09698435344

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026