Skip to content

Comparison Between Two Drugs As Adjuvant To Local Anaesthetic In Ultrasound Guided Regional Anaesthesia In Upperlimb Surgeries.

A randomized prospective comparative study of effect of ketamine versus hyaluronidase as an adjuvant to bupivacaine in ultrasound guided supraclavicular brachial plexus block for upper limb surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/052378
Enrollment
90
Registered
2023-05-08
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: BRACHIAL PLEXUS BLOCK: USG GUIDED SUPRACLAVICULAR APPROACH TO BRACHIAL PLEXUS BLOCK,USING 20ML BUPIVACAINE 0.5%(P) WITH 3ML NS Control Intervention1: KETAMINE: 2MG/KG Ketamine added as

Sponsors

ekta bharti
Lead Sponsor
SUBHARTI MEDICAL COLLEGE
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade1 and 2 Forearm surgeries Weight 40-60kgs will be included in the study informed consent

Exclusion criteria

Exclusion criteria: Morbid obesity (BMI > 40 kg/m2) patient with physical status of ASA III or greater History of lung disease, cardiac disease,hepatic or renal impairment, neuromuscular disorder History of chronic pain or psychiatric disorder Drug or alcohol abuse Hypersensitivity to local anaesthetics Patients with peripheral neuropathies and coagulation disorder Patients with history of seizures Patients with history of brachial plexus injury,clavicle fracture or chest or shoulder deformities on the operative side Pregnant women

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the effect of ketamine versus hyaluronidase with bupivacaine on onset and duration of sensory block(duration of anaelgesia) and motor block. To evaluate and compare the effect of ketamine versus hyaluronidase with bupivacaine on hemodynamics. Timepoint: The sensory and motor block onset will be assessed every 5 minutes upto 30 minutes. Hemodynamics will be assesed at 1st,2nd,3rd,4th,5th,6th,8th,10th,12th, and 24th postoperative hour.

Secondary

MeasureTime frame
â?¢ To evaluate and compare the effect of ketamine versus hyaluronidase with bupivacaine on postoperative pain scores and rescue analgesic. Timepoint: will be assesed at 1st,2nd,3rd,4th,5th,6th,8th,10th,12th, and 24th postoperative hour.

Countries

India

Contacts

Public ContactEkta Bharti

subharti medical college and hospital

hsminhas28@yahoo.co.in9950797341

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026