Study based on tranexamic acid spray on heart to look for decrease in bleeding after surgery

Topical application of tranexamic acid in the form of mist to reduce postoperative bleeding in off pump CABG procedure

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/05/052353

Enrollment

60

Registered

2023-05-08

Start date

Unknown

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery

Interventions

Intervention1: TRANEXAMIC ACID: TOPICAL TRANEXAMIC ACID APPLICATION TO SEE FOR POSTOPERATIVE BLOOD LOSS Intervention2: DRUG SPRAY: TOPICAL APPLICATION OF 2GM TRANEXAMIC ACID IN THE FORM OF SPRAY ON TH

Sponsors

Kasturba Medical College, Manipal

Lead Sponsor

DR CHANDRIKA J

Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged between 40 and 75 years undergoing elective surgery for off pump CABG procedure

Exclusion criteria

Exclusion criteria: Known allergy to tranexamic acid Redo surgery Coagulopathy Renal failure Emergency surgeries On pump CABG procedure Patient refusal to participant in study LVEF <35%

Design outcomes

Primary

Measure	Time frame
To determine postoperative blood loss in mlTimepoint: Postoperative drain in ml 4th hour 8th hour 12th hour 24th hour	—

Secondary

Measure	Time frame
Haemoglobin level,hematocrit value ,platelet count, international normalized ratio and partial thromboplastin time will be measured before and after surgeryTimepoint: Comparing the values before and 24hours after surgery	—

Countries

India

Contacts

Public ContactDR VIJAYA KUMARA

KMC MANIPAL

vijaya.kumara@manipal.edu8970213332

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026