EFFECT OF INVASIVE VS NON INVASIVE MODE OF HUMIDIFICATION.

A STUDY TO COMPARE NON-INVASIVE(34°C) AND INVASIVE(37°C) MODE OF HUMIDIFICATION DURING NON-INVASIVE VENTILATION IN TERM NEONATE

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/05/052333

Enrollment

104

Registered

2023-05-08

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J988- Other specified respiratory disorders

Interventions

Intervention1: Low temperature and low humidity: Respiratory gases will be delivered at temperature of 34 C and humidity of more than 30mg/L and below 44mg/L Control Intervention1: High temperature an

Eligibility

Inclusion criteria

Inclusion criteria: Term infants admitted in NICU requiring primary non invasive respiratory support

Exclusion criteria

Exclusion criteria: 1.Babies with congenital anomalies 2.Syndromic babies 3.Neonates receiving therapeutic hypothermia 4.Neonates in whom primary mode of respiratory support is invasive

Design outcomes

Primary

Measure	Time frame
Total duration of respiratory support during admission to the NICUTimepoint: Till hospital discharged.	—

Secondary

Measure	Time frame
1. Ventilator Associated Pneumonia 2. Humidity and Temperature at nasopharyngeal level (thermohygrometer) 3. Need of Intubation/ NIV failure 4.Duration of Oxygen support 5.Pulmonary Hemorrhage (Blood secretions in ET) 6.Pulmonary Edema (Radiographic changes) 7. Sepsis (Culture positive) 8. Frequency of suctioning 9. Weight gain or loss Timepoint: till discharge	—

Countries

India

Contacts

Public ContactANSHUL MADAAN

Paramitha Children Hospital

madaan1094anshul@gmail.com6280060939

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026