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Role of dexamethasone in nebulized versus intravenous route in prevention of post operative sore throat

Nebulized Dexamethasone versus intravenous Dexamethasone in prevention of post operative sore throat in patient undergoing endotracheal intubation during general anesthesia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/052307
Enrollment
120
Registered
2023-05-04
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: group intravenous : single dose of intravenous dexamethasone 0.2mg/kg half an prior to induction with general anesthesia Control Intervention1: group A : single dose of lV dexamethaso

Sponsors

Kasturba Medical Colleges
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: •Adult patient aged 18-60 years of either gender •ASA PS grade I/ II scheduled to undergo surgery requiring general anesthesia with duration less than 3hrs

Exclusion criteria

Exclusion criteria: 1. Patient with anticipated difficult airway 2. Patient on steroids 3. Patient on recent history URTI/ LRTI 3.patient requiring more than 2 attempts during intubation 4.patients with history of diabetes mellitus 5. Head neck surgeries 6 Patient in whom Dexamethasone is from surgical side contraindicated

Design outcomes

Primary

MeasureTime frame
Assessment of post operative sore throat .Timepoint: Presence of sore throat and grading will be done at 12 hrs , 24 hrs and 48 hrs

Secondary

MeasureTime frame
1. To note the presence of cough and hoarseness of voice 2. Pre and post operative blood sugar levels Timepoint: Presence of sore throat and grading will be done at 12 hrs , 24 hrs and 48 hrs

Countries

India

Contacts

Public ContactDr Shweta Sinha

Kasturba Medical College Manipal

drlaxmishenoy@gmail.com8073822017

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026