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Comparative evaluation of dentinal hypersensitivity by a nano-hydroxyapatite and herbal formulated desensitizing toothpaste in patients with dentinal hypersensitivity: A randomized controlled trial

Comparative evaluation of dentinal hypersensitivity by a nano-hydroxyapatite and herbal formulated desensitizing toothpaste in patients with dentinal hypersensitivity: A randomized controlled trial.

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/052295
Enrollment
75
Registered
2023-05-04
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K038- Other specified diseases of hard tissues of teeth

Interventions

None listed

Sponsors

Dr Sumedha Meenal Thosar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients with dentine hypersensitivity in single or multirooted teeth on consumption of cold food stuff, air blast and on slightly moving the probe over the defect surface. 2) Patient with age group of 25-50 years. 3) Patients with sensitivity score > 2 on the visual analogue scale (VAS) 4) Patient having good general and periodontal health (no probing depth exceeding 4 mm and no bleeding on probing); 5)Those patients that have recession of gingiva 6)Teeth with erosion and abrasion. 7)Patient willing to give consent for the study.

Exclusion criteria

Exclusion criteria: 1) Teeth with dental caries or extensive restoration (involving more than 50% of the tooth structure), which might have an abnormal pulpal response; 2) Destructive periodontal diseases; 3) Patients with chronic systemic diseases associated with intermittent episodes of constant daily pain. 4) Tooth mobility > grade I. 5) Patients undergone vital tooth bleaching or orthodontic appliance treatment within previous three months. 6) Patients who had used desensitising agents in past six months. 7) Patients with pregnancy or in lactating period. 8) Patients who smoke or do alcohol abuse.

Design outcomes

Primary

MeasureTime frame
To evaluate difference in relief of dentinal hypersensitivity using a nano-hydroxyapatite and herbal desensitizing tooth paste as compared to control group over a period of 8 weeks in patients with dentinal hypersensitivity.Timepoint: baseline, 1 week, 4 weeks, 8 weeks from baseline

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Sumedha Meenal Thosar

MGV KBH Dental College and Hospital , Nashik

drsamahale@gmail.com9422764080

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026