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Best and safe way to use vecuronium- bolus vs infusion

Continuous Infusion Vs. Intermittent Goal Directed Administration of Vecuronium Bromide- A Double Blinded Randomised Controlled Study.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/052287
Enrollment
80
Registered
2023-05-03
Start date
Unknown
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: goal directed bolus: Will Receive Vecuronium Loading Dose Of - 0.1 mg/kg and intermittent bolus dose of – 0.025mg/kg only when Train of Four (TOF) count =1/4 (TOF monitoring will be don

Sponsors

Goa Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age: 20-60 years 2. Body Mass Index (BMI): 18.5-29.9 3. American society of Anaesthesiologists physical status (ASA) I and II patients 4. Adequately Nil by Mouth. 5. Patients undergoing elective and emergency surgeries of duration 2hrs and above.

Exclusion criteria

Exclusion criteria: Patients with 1. Liver disorders 2. Neuromuscular Disorders 3. Renal disorders 4. Acid base or electrolyte imbalances 5. Anticipated difficult airway.

Design outcomes

Primary

MeasureTime frame
To compare the amount of Vecuronium used during continuous infusion (0.75ug/kg/min) with that used during the intermittent goal directed bolus (0.025mg/kg).Timepoint: induction time reversal time

Secondary

MeasureTime frame
To compare the characteristics of recovery from neuromuscular blockade after injecting Vecuronium either by continuous infusion or goal directed bolus.Timepoint: induction time reversal time reversal to 25%TOF time reversal to 50% TOF time reversal to 75% TOF time

Countries

India

Contacts

Public ContactDr Abhinandan Annasab Chougale

Goa Medical College

pabi1984@yahoo.com9823745367

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026