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A comparative study to evaluate the anti-inflammatory and analgesic activity of flavonoids and serratiopeptidase in patients undergoing mandibular third molar surgeryâ??A Randomized Controlled Trial

A comparative study to evaluate the anti-inflammatory and analgesic activity of flavonoids versus serratiopeptidase in combination with diclofenac in patients undergoing mandibular third molar surgeryâ??A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/052286
Enrollment
92
Registered
2023-05-03
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K006- Disturbances in tooth eruption

Interventions

Intervention1: Drug: Drug - Serratiopeptidase in combination with Diclofenac and Flavonoids in combination with Diclofenac Route : Oral Duration : 3 Days Dosage for Serratiopeptidase in combinatio

Sponsors

Dr Nitin B
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA I patients in the age group of 18- 40 years with either gender 2. All impacted mandibular third molars requiring surgical extraction 3. CLASS I, CLASS II, POSITION-A and POSITION-B Impacted third molar According to Pell and Gregory classification 4.Patient willing to participate in the study

Exclusion criteria

Exclusion criteria: 1.Acute infection 2.Patient allergic to administrated drugs 3.Patients with Gastric Ulcers 4.Patient with bleeding disorders 5.Pregnancy and Lactating women 6.Immunocompromised patient Mentally challenged patient

Design outcomes

Primary

MeasureTime frame
Primary Outcome: Pain Secondary Outcome: Swelling and TrismusTimepoint: Both Primary and Secondary outcomes are measured on the pre operative day (Day 0) and post operative days (Day 1and Day 3) that is during the course of the intervention administered and post operative days (Day 7 and Day 12) for follow up

Secondary

MeasureTime frame
Swelling TrismusTimepoint: 1ST POST-OP DAY 3RD POST OP DAY 7TH POST OP DAY 12TH POST OP DAY

Countries

India

Contacts

Public ContactDr Nitin B

Sri Venkateshwaraa Dental College

omfssvdc@gmail.com9344235655

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026