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How renin angiotensin system gets affected in cardiac autonomic neuropathy by exercise and yoga in diabetes patients?

Effect of exercise and Yoga program on renin-angiotensin mechanism in cardiac autonomic neuropathy in Diabetes mellitus patients.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/052268
Enrollment
150
Registered
2023-05-03
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E115- Type 2 diabetes mellitus with circulatory complications

Interventions

Intervention1: Exercise and yoga program: Group 1 - supervised aerobic exercise program for 6 months Group2- supervised yoga program for 6 months Intervention2: Group 1- to undergo a supervised aerobi

Sponsors

DHR-GIA (Department of Health research grant in aid scheme)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Diagnosed case cardiac autonomic neuropathy in diabetes mellitus patients

Exclusion criteria

Exclusion criteria: End-stage renal disease • Patient on ACE inhibitors • Known case of heart disease • Uncontrolled hypertension • Uncontrolled diabetes mellitus • Chronic alcoholics • Any neuromuscular disorder not allowing to participate in exercise/yoga program

Design outcomes

Primary

MeasureTime frame
To study the effect of a 6-month supervised exercise program/ Yoga program on cardiac autonomic neuropathy (CAN) status in a diagnosed case of CAN in Diabetes mellitus patients. Timepoint: both groups would undergo baseline assessments (0 days) and reassessment at the end of the 6 months.—

Secondary

MeasureTime frame
â?¢ To compare the effect of a 6-month supervised exercise program / Yoga program on fitness parameters in a diagnosed case of CAN in Diabetes mellitus patients with that of baseline.Timepoint: Both groups would undergo baseline assessments (0 days) and reassessment at the end of the 6 months.;â?¢ To compare the effect of a 6-month supervised exercise program/Yoga program on Plasma renin, Serum aldosterone, serum ADH, Angiotensin II, ACE, and Angiotensin (1-7) in a diagnosed case of CAN in Diabetes mellitus patients with that baseline.Timepoint: Both groups would undergo baseline assessments (0 days) and reassessment at the end of the 6 months.;â?¢ To evaluate the effect of a 6-month supervised exercise program/ Yoga program on Serum insulin, Serum C peptide, HbA1c, and glucose level in a diagnosed case of CAN in Diabetes mellitus patients.Timepoint: Both groups would undergo baseline assessments (0 days) and reassessment at the end of the 6 months.—

Countries

India

Contacts

Public ContactDr Sandip M Hulke

AIIMS Bhopal

sandip.physiology@aiimsbhopal.edu.in9039769805

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026