Health Condition 1: K860- Alcohol-induced chronic pancreatitis
Conditions
Interventions
Intervention1: SURGICAL MANGEMENT in EARLY CHRONIC PANCREAITIS WITH NON-DEBILITATING PAIN: Patients in this group are diagnosed cases of chronic pancreatitis as per inclusion criteria with early non d
Sponsors
Department of surgical gastroenterology.
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria Age > 18 years typical clinical history of chronic pancreatitis ? one or more of the following additional criteria for the diagnosis of CP: 1. Pancreatic calcifications on CT or MRI imaging. 2. Moderate or marked ductal lesions on endoscopic retrograde cholangiopancreatography (ERCP) or magnetic resonance cholangiopancreatography (MRCP) imaging. 3. Marked and persistent exocrine insufficiency (defined as: a. pancreatic steatorrhea clearly relieved by enzyme supplementation, and/or b. fecal elastase levels of = 200 micro gram/gram) 4. Dilated pancreatic duct: dilated pancreatic duct of = 5 mm, with or without enlargement of the pancreatic head. 5. Presence of moderate, non-debilitating pain FOR EARLY SURGERY GROUP 6 Presence of debilitating pain not amenable to strong opiods for standard surgery group
Exclusion criteria
Exclusion criteria: Exclusion criteria 1. History of prolonged need of opioids- weak opioids for CP for a total period of 6 months in the last 2 years. 2. Previous pancreatic surgery 3. Previous endoscopic dilatation or stenting of the pancreatic duct /biliary 4. Autoimmune pancreatitis 5. Stones and strictures exclusively located in the tail of the pancreas 6. Fully impacted stones casting the entire main pancreatic duct (from head to tail) and possibly side branches 7. Suspected or confirmed pancreatic malignancy 8. Life expectancy of 9. Presence of duodenal obstruction necessitating surgery. 10. Presence of a pseudocyst larger than 6 cm necessitating intervention. 11. severe portal hypertension due to occluded portal vein 12. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To comparison of pain score after early surgery in CP with current Standard management (late surgery).Timepoint: 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To assesses the quality of life, post procedural complications, disease progression, exocrine and endocrine dysfunction during the follow up period.Timepoint: 2 years | — |
Countries
India
Contacts
Public Contactvivek g nath
Department of surgical Gastroenterology, Thanjavur medical college
Outcome results
None listed