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To compare effect of adding drugs like dexamethasone and dexmedetomidine as additives in upper limb nerve block surgeries in reducing Rebound postoperative pain in patients

COMPARISON OF PERINEURAL DEXAMETHASONE AND DEXMEDETOMIDINE AS ADJUVANTS IN REDUCING REBOUND PAIN IN PATIENTS UNDERGOING PERIPHERAL NERVE BLOCK:A DOUBLE BLIND RANDOMISED CONTROLLED STUDY

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/05/052194
Enrollment
75
Registered
2023-05-02
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: dexamethasone: To add dexamethasone 2ml(8mg) with 28 ml of 0.75% Ropivacaine given for nerve block by supraclavicular approach once before start of surgery Intervention2: DEXMEDETOMID

Sponsors

Dr Abinaya K
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients belonging to ASA physical status 1and 2 2.Patients giving informed valid written consent 3.patients undergoing elective orthopaedic upper limb surgery

Exclusion criteria

Exclusion criteria: 1.Patients with coagulopathies, neurological disorder 2.Patients having hypersensitivity to any of study drugs

Design outcomes

Primary

MeasureTime frame
To assess the rebound pain in three study groups (dexamethasone as adjuvant, dexmedetomidine as adjuvant and no adjuvant added) and compare numerical rating scoresTimepoint: Rebound pain will be monitored for 48 hours post placement of block

Secondary

MeasureTime frame
To assess time taken for resolution of nerve blocks Timepoint: Assessment of return of motor movement and sensation for 48 hours in the postoperative period

Countries

India

Contacts

Public ContactDr Madhuri S Kurdi

Karnataka institute of medical sciences

drmadhuri_kurdi@yahoo.com9449590556

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026