Health Condition 1: Z991- Dependence on respirator
Conditions
Interventions
Intervention1: Lung and abdominal ultrasound: 120 minutes after spontaneous breathing trial(SBT) initiation, Lung ultrasound score (LUS), inspiratory muscle (diaphragm) and abdominal expiratory muscle
Sponsors
PGIMER Dr RML Hospital New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: On invasive mechanical ventilation for more than 48 hours duration and put on spontaneous breathing trial (SBT) prior to extubation
Exclusion criteria
Exclusion criteria: 1.Short-term mechanical ventilation ( 2.Refusal of consent 3.Patients with spinal cord injuries above the t8 level 4.Presence of significant cardiac arrhythmia 5.Patients with pre-existing diaphragmatic disorders 6.Patients with any neuromuscular weakness or ICU-acquired neuromyopathy 7.Planned non-invasive ventilation(NIV) following extubation 8.Chest or abdominal trauma 9.Patients with distorted abdominal wall anatomy or localized fluid collections in the abdomen, hernias, abdominal wall hematomas, inguinal masses, femoral hernias & abdominal surgeries 10.Pregnant patients 11.Poor ultrasound window
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Combination of lung ultrasound score (LUS), diaphragmatic thickening fraction (DTF), diaphragmatic excursion(DE), internal oblique thickening fraction and diaphragmatic rapid shallow breathing index(D-RSBI) in prediction of successful weaning and extubation failure.Timepoint: 120 minutes following successful spontaneous breathing trial | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Estimate cut-off sensitivity and specificity of internal oblique thickening fraction and diaphragmatic RSBI to predict successful weaning. 2. Compose a comprehensive score based upon ultrasound based weaning indices for prediction of successful weaning. Timepoint: 12 months | — |
Countries
India
Contacts
Public ContactDr Jyotirmaya Prakash Pati
PGIMER, Dr RML hospital
Outcome results
None listed