Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Dexmedetomidine: Nebulised dexmedetomidine 1mcg/kg will be given 30 minutes before induction.
Control Intervention1: Dexmedetomidine: Intravenous dexmedetomidine 1mcg/kg will be given 3
Sponsors
Reshma B M
M Salim Iqbal
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective surgeries under general anaesthesia 2. Patients belonging to American Society of Anaesthesiologists Physical Status (ASA-PS) 1 and 2
Exclusion criteria
Exclusion criteria: 1. Patient refusal 2. Patient allergic to study drug 3. BMI > 30 kg/m2. 4. Patients with difficulty airway, unanticipated difficult laryngoscopy and intubation ( lasting > 15 seconds or more than 2 attempts at intubation) 5. Pregnancy and lactation. 6. Patient on opioids, sedatives, or beta blockers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To assess the effect of nebulized and intravenous dexmedetomidine on mean arterial pressure response following laryngoscopy.Timepoint: 1. Following laryngoscopy at baseline, every minute for 5 minutes and at 10th minute. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To determine the dose sparing effect of induction dose of propofol. 2. To assess the sedation scores preoperatively, using Modified Ramsay sedation score. 3.To assess for side effects if any.Timepoint: 1. After induction of anaesthesia. 2. Every 5 minutes after drug administration for 30 minutes. 3. From start of drug administration till end of surgery. (every 5 minutes) | — |
Countries
India
Contacts
Public ContactReshma B M
Dr B R Ambedkar medical college and hospital
Outcome results
None listed