Trial of tDCS in adolescents with depression as early augmentation

RANDOMISED, SINGLE BLIND, CONTROL TRIAL OF TRANSCRANIAL DIRECT CURRENT STIMULATION IN ADOLESCENTS WITH MAJOR DEPRESSIVE DISORDER AS EARLY AUGMENTATION

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/04/052144

Enrollment

Registered

2023-04-28

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F32- Major depressive disorder, singleepisode

Interventions

Intervention1: Active Transcranial Direct Current Stimulation: A total of 10 sessions (on a daily basis) of tDCS will be delivered over a period of two weeks following a uniform treatment protocol as

Eligibility

Inclusion criteria

Inclusion criteria: 1. Informed consent from the parent/guardian and assent of the patient 2. Diagnosed with MDD (As per DSM-5 criteria) 3. Drug naïve (For at least last 1 month)

Exclusion criteria

Exclusion criteria: 1. Treatment Resistant Depression 2. Psychotic Depression 3. Suicidality 4. Medical comorbidities that need immediate attention 5. Any contraindication to tDCS 6. Any other psychiatric comorbidity (except tobacco use disorder)

Design outcomes

Primary

Measure	Time frame
Reduction of BDI scoresTimepoint: Reduction of BDI scores at baseline, 2 weeks and 6 weeks	—

Secondary

Measure	Time frame
1. t-DCS side effect checklist 2. Change in scales of Beck Anxiety Inventory (BAI) and scores of Executive Interview (EXIT-25)Timepoint: 1. t-DCS side effect checklist assessed after 10 sessions 2. BAI and EXIT-25 at baseline, 2 weeks and 6 weeks	—

Countries

India

Contacts

Public ContactSaumya Upadhyay

King Georges Medical University

drsujita@gmail.com9956273747

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026