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comparing the rate of fibroblast migration using Fibroblast growth factor and L-PRF over 3 days

Comparative evaluation of efficacy of L-PRF or fibroblast growth factor on gingival fibroblast migration- A controlled ex-vivo microscopic study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/04/052125
Enrollment
5
Registered
2023-04-28
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K051- Chronic gingivitis

Interventions

Intervention1: Leukocyte platelet rich fibrin: Leukocyte platelet rich fibrin membrane will be made by centrifuging 10 cc blood from 1 volunteer and membrane will be placed on the fibroblast culture p

Sponsors

Dr Mugdha Mangaonkar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: A) Healthy volunteers who are who are willing to participate. B) Age group 18-60 years

Exclusion criteria

Exclusion criteria: A) Volunteers with any systemic diseases. B) Volunteers who have received antibiotic therapy in last 3 months. C) Volunteers taking anti-coagulant drugs. D) Volunteers with poor haemogram, low haemoglobin levels. E) Volunteers who are pregnant or lactating. F) Volunteers who are smokers or any other deleterious habits.

Design outcomes

Primary

MeasureTime frame
Leukocyte platelet rich fibrin membrane will have effect on the gingival fibroblast migration. Timepoint: 24 hours 48 hours 72 hours—

Secondary

MeasureTime frame
Fibroblast growth factor II will have effect on the gingival fibroblast migration. Timepoint: 24 hours 48 hours 72 hours—

Countries

India

Contacts

Public ContactDr Mugdha Mangaonkar

MGM dental college and hospital Kamothe

khistesujeet@gmail.com9833908511

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026