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Comparing pupil size with heart rate and blood pressure during anaesthesia

Correlation between ultrasonographic pupillary dilation reflex with haemodynamic response during anaesthesia induction and surgical incision: prospective observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/04/052102
Enrollment
85
Registered
2023-04-28
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

ALL INDIA INSTITUTE OF MEDICAL SCIENCES RISHIKESH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesia Grade I and Grade II patients undergoing laparoscopic cholecystectomy under general anaesthesia.

Exclusion criteria

Exclusion criteria: Patient refusal to participate in study Patients undergoing ophthalmic, neuro and/or facial surgery Patients with eye injury History of ophthalmic surgery known pupillary reflex disorders. Cranial nerve lesions Preoperative use of topically interfering eye drops (Atropine , Phenylephrine) Receiving drug which can interfere with PDR

Design outcomes

Primary

MeasureTime frame
To correlate the amplitude of PDR (%) with changes in heart rate (beats/min) during surgical incision.Timepoint: 1 minute after surgical incision.—

Secondary

MeasureTime frame
To assess the correlation between PDR (%) and BIS (Bispectral Index) for depth of anaesthesia assessment during intraoperative period.Timepoint: 1 minute after endotracheal intubation, 1 minute after surgical incision and every 30 minutes after surgical incision;To correlate the amplitude of PDR (%) with changes in blood pressure (mm of Hg) during during endotracheal intubation and surgical incisionTimepoint: 1 minute after endotracheal intubation and 1 minute after surgical incision;To correlate the amplitude of PDR (%) with changes in heart rate (beats/min) and blood pressure during maintenance of anaesthesia.Timepoint: Every 30 minutes after surgical incision till completion of surgery;To correlate the amplitude of PDR (%) with changes in heart rate (beats/min) during endotracheal intubation. Timepoint: 1 minute after endotracheal intubation;To correlate the amplitude of PDR with NRS (Numerical Rating Scale) score for pain assessment in post operative recovery roomTimepoint: Every 10 minutes in post anaesthesia care unit till 30 minutes.;To correlate the PDR (%) with pulsatility index (PI) during intraoperative periodTimepoint: 1 minute after endotracheal intubation, 1 minute after surgical incision and every 30 minutes after surgical incision—

Countries

India

Contacts

Public ContactDr Deepak Singla

AIIMS Rishikesh

deepak10.4u@gmail.com9068504999

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026