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Comparision of morphine in two different doses as adjuvant to hyperbaric ropivacaine versus plain hyperbaric ropivacaine in lower limb surgeries.

Comparision of intrathecal morphine in two different doses as an adjuvant to hyperbaric ropivacaine versus plain hyperbaric ropivacaine in lower limb orthopedic surgeries double blind randomized controlled study

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/04/052091
Enrollment
114
Registered
2023-04-28
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M849- Disorder of continuity of bone, unspecified Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Group RM1: The patient will be administered 3 ml (22.5 mg) of hyperbaric ropivacaine (0.75%) with 100µgm morphine intrathecally. Control Intervention1: Group R: The patient will be a

Sponsors

Bhagat phool singh govt medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American society of Anaesthesiologists (ASA) grade I/II patients undergoing lower limb orthopedic surgical procedures under spinal anaesthesia. Age group:18 - 65 years of any sex. Patient voluntary participate in the study.

Exclusion criteria

Exclusion criteria: Contraindication to spinal anaesthesia. History of allergy to morphine or ropivacaine. Patients with severe psychiatric disorder such as depression, dementia or drugs which could interfere with the comprehension of the study. Patients with history of any cardiac disease, coagulopathy or any respiratory disorder.

Design outcomes

Primary

MeasureTime frame
Primary outcome will be to evaluate the need for first analgesic dose.Timepoint: Post operatively after 2 hours.

Secondary

MeasureTime frame
the secondary outcome will be to assess the onset and duration of sensory and motor blockade along with hemodynamic parameters and side effectsTimepoint: Immediately after spinal anaesthesia

Countries

India

Contacts

Public ContactDr Shivani Meena

Bhagat Phool Singh Govt Medical College Khanpur Kalan Sonepat Haryana

sarv.mlb007@gmail.com9728800122

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026