None listed
Conditions
Interventions
Intervention1: Tvaksh Moisguard DN: An amount of 2 mg (µl) per cm2 has to be applied on each randomized test site. The product has to be dispensed from a positive displacement pipette/ disposable syri
Sponsors
Abbott India Limited
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy female subjects, as determined from a recent medical history. 2. Subjects in the age group of 18-45 years (both ages inclusive). 3. Subjects who present normal to dry skin on the forearm (corneometer value of 35 as maximum) 4. Healthy skin in the test sites. 5. Subjects willing to give voluntary written informed consent and agree to come for regular follow-up. 6. Subjects willing to abide by and comply with the study protocol. 7. Subjects who are willing not to participate in any other clinical study during participation in the current study.
Exclusion criteria
Exclusion criteria: 1. Excessive hair on the test site 2. A known history or present condition of an allergic response to any cosmetic products. 3. Change personal nutrition habits as well as sports habits 4. Start or change their oral hormonal treatment or their oral contraception 5. Subject having active skin diseases (e.g., active atopic dermatitis, pigmented contact dermatitis or other cutaneous manifestations), which will interfere with the assessment. 6. Subjects on oral medications (e.g. steroids, anti-oxidant) which will compromise the study. 7. Subjects had cancer in the last 10 years 8. Subjects with wounds, sunburn, scars, tattoos or piercings at the skin test site(s) 9. Subjects with application of ointments, creams etc. for antibacterial, anti-allergic or immunosuppressive treatment of the skin at the test site(s) 10. Systemic treatment which may modify the cutaneous state on the day of inclusion or in the previous 30 days, including retinoid therapy. 11. History of intense sun exposure and/ photo toxicity/allergy. 12. Female subjects who are pregnant, lactating or nursing. 13. Chronic illness which may influence the cutaneous state. 14. Subject participating in any other cosmetic or therapeutic trial. 15. Any underlying uncontrolled medical illness including diabetes mellitus, hypertension, liver disease or history of alcoholism, HIV, hepatitis, or any other serious medical illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To evaluate and compare skin moisturization using Corneometer – CM 825 with a single application of the test product in comparison to the baseline and untreated control. 2. To evaluate the retention of skin moisturization for immediate, 4 hours, 8 hours, and 24 hours using Corneometer – CM 825 with a single application of the test product in comparison to the untreated site. 3. To evaluate the deep moisturization: TEWL with a single application of the test product in comparison to the untreated site. 4. To measure and compare TEWL at immediate, 4 hours, 8 hours, and 24 hours with a single application of the test product in comparison to the baseline and untreated control.Timepoint: Baseline, immediate, 4 hours, 8 hours and 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the efficacy based on the dermatological visual assessment at immediate, 4 hours, 8 hours, and 24 hours with a single application of the test product compared to the baseline and untreated control.Timepoint: Baseline, immediate, 4 hours, 8 hours and 24 hours | — |
Countries
India
Contacts
Public ContactDr Mukesh Ramnane
MS Clinical Research Pvt Ltd
Outcome results
None listed