Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: comparison of transdermal buprenorphine and fentanyl for postoperative analgesia in patients undergoing infraumblical and lower limb orthopedic surgeries: TECHNIQUE
Pre-operatively:
P
Sponsors
Dr Harjinder Kaur
Eligibility
Inclusion criteria
Inclusion criteria: 1. Men and women between 18-60 years, who have given their consent 2. ASA classes I and II 3.Posted for infraumbilical surgeries like inguinal hernia repair, haemorroidectomy, hydrocele surgery, surgery for varicose veins and lower limb orthopaedic surgeries
Exclusion criteria
Exclusion criteria: 1. History of allergy to opioids 2. History of/ongoing drug abuse 3. Patients who are already using a transdermal opioid patch 4. Pregnant patients 5. Patients taking opioids, NSAIDS, or any pain medication for more than 3 months 6. Patients on antiepileptics or antidepressants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To compare the efficacy of the study drugs in terms of duration of analgesia in infraumbilical and lower limb orthopaedic surgeries up to 48 hours. 2.Total rescue analgesia received in 48 hours. Timepoint: 1.To compare the efficacy of the study drugs in terms of duration of analgesia will be measured every 2 hourly upto 12 hours and then 4 hourly upto 48 hours 2.Total rescue analgesia received in 48 hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Hemodynamic variability 2. Side effects like pruritus, respiratory depression (SpO2 less than 90% or respiratory rate 8), sedation (as per Ramsay Sedation Scale score of 5 or 6), and postoperative nausea and vomiting. Outcomes will be noted and analyzed at different timelines for 48 hours. Timepoint: 48 hours | — |
Countries
India
Contacts
Public ContactDr Harjinder Kaur
government medical college, amritsar
Outcome results
None listed