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Study on Hyperbaric (0.75%)ROPIVACAINE versus Hyperbaric (0.5%)BUPIVACAINE For lower limb surgeries Under Spinal Anaesthesia

A Comparative Evaluation of Hyperbaric (0.75%) ROPIVACAINE versus Hyperbaric (0.5%) BUPIVACAINE For lower limb surgeries Under Spinal Anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/04/052039
Enrollment
138
Registered
2023-04-27
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: Hyperbaric (0.75%) Ropivacaine and Hyperbaric (0.5%) Bupivacaine: 25 G LP spinal needle used for patients under group B to recieve 3ml of hyperbaric (0.5%) Bupivacaine for spina

Sponsors

DR VIKAS MISHRA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients weighing between 45kg to 80 kg with height between 160cm to 185cm undergoing lower limb surgeries.

Exclusion criteria

Exclusion criteria: 1.Unwilling patients 2.Psychiatric diseases 3.Emergency surgeries 4.History of drug abuse and known case of hypersensitivity to local anaesthesia or adjuvants 5.Patient with medical complications like raised intracranial tension,anaemia, heart disease, diabetes mellitus, severe hypovolemia, shock,septicaemia and hypertension 6.Patients with coagulation disorders or an anticoagulant therapy 7.Local infection at the proposed site of puncture for spinal anaesthesia 8. Spinal deformities like kypho-scoliosis, lordosis etc. 9. Heart block or Dysrrhythmia or patients on therapy with adrenergic receptor agonist/antagonist

Design outcomes

Primary

MeasureTime frame
sensory block will be assessed by pin prick test and motor block assessed by modified Bromage scale.Timepoint: Time1, at which subarachnoid block given(T1);Time2 at which T10 sensory block achieved (T2);Time3 at which motor block achieved (T3); Time4 at which complete regression of sensory block (T4); Time5 at which complete regression of motor block(T5)—

Secondary

MeasureTime frame
comparison of clinical efficacy and safety of hyperbaric 0.75% ropivacaine and 0.5% hyperbaric bupivacaine on hemodynamic changes and adverse effects,if any.Timepoint: five time points: time 1, at which subarachnoid block given(T1); time 2, at which T10 sensory block achieved (T2); time 3, at which motor block achieved (T3); time 4, at which complete regression of sensory block (T4), time 5, at which complete regression of motor block (T5).—

Countries

India

Contacts

Public ContactDR JAYESH SHAKEET

K D MEDICAL COLLEGE HOSPITAL AND RESEARCH CENTRE

drjayeshshakeet@gmail.com9717983199

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026