Study to know and compare the sequence of recovery of consciousness after general anaesthesia with two different inhalational anaesthetics in patients posted for laparoscopic gall bladder removal surgeries

A randomised study to compare the recovery profile of cognitive functions in patients undergoing laparoscopic cholecystectomy under desflurane versus sevoflurane based general anaesthesia

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/04/052009

Enrollment

Registered

2023-04-26

Start date

Unknown

Completion date

Unknown

Last updated

2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: K819- Cholecystitis, unspecified

Interventions

Intervention1: General Anaesthesia: General anaesthesia using either desflurane or sevoflurane was given in two groups of patients posted for laparoscopic cholecystectomy Control Intervention1: desflu

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 and 2 Minimum Educational Qualification -Primary Education Patients posted for laparoscopic cholecystectomy under GA

Exclusion criteria

Exclusion criteria: Age less than 18 or more than 50 years History of alcohol or drug abuse History of neuropsychiatric disorder Illiterate GCS <15

Design outcomes

Primary

Measure	Time frame
To compare the cognitive functions after anaesthesia recovery from baseline values in both casesTimepoint: In PACU, 30 minutes after reversal from GA, patientâ??s cognitive function will be re-assessed by the investigator who is unaware of the anaesthetic group the patient belongs to. Then cognitive function will be assessed again twice at 1 hour interval, after 90 and 150 minutes after reversal. Baseline as well as Post anaesthesia scores of all six domains will be recorded at 3 different time points after recovery from general anaesthesia will be compared and analysed.	—

Measure

Time frame

To compare the cognitive functions after anaesthesia recovery from baseline values in both casesTimepoint: In PACU, 30 minutes after reversal from GA, patientâ??s cognitive function will be re-assessed by the investigator who is unaware of the anaesthetic group the patient belongs to. Then cognitive function will be assessed again twice at 1 hour interval, after 90 and 150 minutes after reversal. Baseline as well as Post anaesthesia scores of all six domains will be recorded at 3 different time points after recovery from general anaesthesia will be compared and analysed.

—

Secondary

Measure	Time frame
To assess the sequence of cognitive recovery after recovering from anaesthesiaTimepoint: In PACU, 30 minutes after reversal from GA, patientâ??s cognitive function will be re-assessed by the investigator who is unaware of the anaesthetic group the patient belongs to. Then cognitive function will be assessed again twice at 1 hour interval, after 90 and 150 minutes after reversal. Baseline as well as Post anaesthesia scores of all six domains will be recorded at 3 different time points after recovery from general anaesthesia will be compared and analysed.	—

Measure

Time frame

To assess the sequence of cognitive recovery after recovering from anaesthesiaTimepoint: In PACU, 30 minutes after reversal from GA, patientâ??s cognitive function will be re-assessed by the investigator who is unaware of the anaesthetic group the patient belongs to. Then cognitive function will be assessed again twice at 1 hour interval, after 90 and 150 minutes after reversal. Baseline as well as Post anaesthesia scores of all six domains will be recorded at 3 different time points after recovery from general anaesthesia will be compared and analysed.

—

Countries

India

Contacts

Public ContactDr Nidhi Arun

Indira Gandhi Institute Of Medical Sciences

vermaankita72@gmail.com8252510939

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026