FindTrial
Sign In

To see the effect of Pregabalin as premedication before surgery for reduction of incidence of Post Operative Nausea Vomiting in Laparoscopic Surgeries.

Does oral pregabalin as premedication 1 hour before the surgery reduce the Incidence of post operative nausea vomiting in laparoscopic surgeries? : A Prospective randomized double blind placebo controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/04/051980
Enrollment
70
Registered
2023-04-26
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Pregabalin: Tab Pregabalin 150 mg 1 hour before surgery Oral Control Intervention1: Placebo (Multivitamin): Placebo 1 hour before surgery

Sponsors

Dr Ramesh Kumar P B
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with ASA 1 & 2 2. Laparoscopic surgeries of 1 to 3 hours duration

Exclusion criteria

Exclusion criteria: 1. Surgeries with duration more than 3 hours and less than 1 hour 2. ASA 3 & 4 3. History of Postoperative nausea vomiting 4. History of motion sickness 5. Hypersensitivity to Pregabalin 6. Patients already on Pregabalin / GABA agonist / GABA mimetics

Design outcomes

Primary

MeasureTime frame
Post Operative Nausea VomitingTimepoint: 12 hours after surgery—

Secondary

MeasureTime frame
Hemodynamic response of direct laryngoscopy and endotracheal intubationTimepoint: 1 minute, 3 minutes, 5 minutes, 10 minutes, 15 minutes—

Countries

India

Contacts

Public ContactDr Rajmane Vishal Vaibhav

BGS Global Institute of Medical Sciences

Odeyarshwetha@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026