Health Condition 1: I503- Diastolic (congestive) heart failure
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients with unexplained dyspnea or fatigue with LV ejection fraction of more than or equal to 50% on transthoracic echocardiography with no apparent cause of HF symptoms other than HFpEF 2) Age >= 35 years
Exclusion criteria
Exclusion criteria: 1) Significant valvular disease: severe AS,AR,MS,MR 2) Pericardial diseases 3) Prosthetic heart valve or prosthetic ring 4) Obstructive heart lesions(myxomas) 5) Congenital heart disease 6) Severe anaemia 7) Severe COPD 8) Poor acoustic window
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| myocardial work by echocardiography in patients with heart failure with preserved ejection fraction.Timepoint: at baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| correlation of myocardial work and global longitudinal strain(GLS) with NT Pro BNP levels and pulmonary capillary wedge pressure(PCWP).Timepoint: at baseline | — |
Countries
India
Contacts
VMMC and SJH