A clinical study, to compare the effect of two ayurvedic medicines (Shothkalanal ras and Punarnvastak kwath) to treat Primary Hypothyroidism.

Clinical comparative study of Shothkalanal ras & Punarnavastak kwath in the management of Primary Hypothyroidism.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/04/051967

Enrollment

Registered

2023-04-25

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: - Health Condition 3: E039- Hypothyroidism, unspecified Health Condition 4: E039- Hypothyroidism, unspecified Health Condition 5: E039- Hypothyroidism, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1) Age between 18-50 years25(much variations have been found in normal values of Thyroid profile below18 and above 50 yrs of age)26 2) Elevated level of Serum TSH - 5.0 µU/ml to 15 µU/ml (Normal value 0.4 to 5.0 µU/ml SI Units 0.4-5.0mU/L)27 3) Low serumT3- Less than 77 ng / dl or in normal range. (no specific range defined for below normal) (Normal value 77 to 135 ng /dl SI Units 1.2-2.1 nmol /L)27 4) Low serum T4 Less than 5.4 µg/dl, (no specific range defined for below normal) (Normal value 5.4 to 11.7 µg/dl SI Units70- 151nmol/L)27

Exclusion criteria

Exclusion criteria: 1) Age below 18 and above 50 years (much variations have been found in normal values of Thyroid profile below18 and above 50 yrs of age)26 2) Patients suffering from goitre (Enlarged thyroid gland) 3) Drug induced Hypothyroidism 4) Major Systemic illness likeTuberculosis. 5) Any CNS disorder e.g. encephalopathy

Design outcomes

Primary

Measure	Time frame
Efficacy of Sothkalanal ras in the management of Primary Hypothyroidism. Efficacy of Punarnavastak kwath in the management of Primary Hypothyroidism. Timepoint: 4 months	—

Secondary

Measure	Time frame
Side effects of trial drugs in long term use. Reappearance of symptoms of Primary Hypothyroidism, if any after follow up.Timepoint: Total clinical study period with follow up 8 months.	—

Countries

India

Contacts

Public ContactDR ANKUR SINGHAL

R.A. Podar Ayurved Medical College, Mumbai

bhaskaresunil14@gmail.com9819165638

Outcome results