Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients of ASA physical status I and II, both gender in the mentioned age group who will give written informed consent.
Exclusion criteria
Exclusion criteria: Patients with ASA physical status III of greater. Severe cardiorespiratory,hepatic,renal,neurological or endocrinal disease. Bradycardia(Heart Rate Pregnant and lactating women. Obesity(BMI >30kg/m2). Diabetes mellitus. Patientswith known hypersensivity of drug allergies. Patients who had taken H2 antagonists,antiemetic or psychoactive medication. Nausea, retching,or vomiting within 48hours before surgery. History of Motion sickness. Patients who refuse to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate and compare complete response to and/or incidence of Post operative nausea and vomiting with dexmedetomidine and dexamethasone seperately.Timepoint: Baseline Before Administration Of Drug After administration of Drug During Intubation After Intubation 45 mins Intraoperatively At the end of Surgery 15 minutes postoperatively 2 hours postoperatively 6 hours postoperatively 12 hours postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare and evaluate incidence of rescue antiemetic used with dexmedetomidine and dexamethasone. To compare and evaluate side effects of dexmedetomidine and dexamethasone. To compare and evaluate patient satisfaction with Post-opeartive Nausea and vomiting.Timepoint: Patients satisfaction score will be recorded 12 hours post-opearatively. | — |
Countries
India
Contacts
Subharti Medical College and Hospital