Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Respiratory support during endotracheal intubation: Respiratory support will be provided in the form of heated humidified high flow nasal cannula (HHHFNC)/
continuous positive airway pr
Sponsors
ALL INDIA INSTITUTE OF MEDICAL SCIENCES, RISHIKESH
POONAM SINGH
Eligibility
Inclusion criteria
Inclusion criteria: Neonates undergoing endotracheal intubation in NICU.
Exclusion criteria
Exclusion criteria: 1. Heart rate 2. Life threatening congenital anomalies 3. Cyanotic congenital heart disease 4. Need for intubation on emergency basis as determined by treating clinician 5. Failure to obtain consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of successful intubation in first attempt without physiological instability (HR100/min and/or decrease in SpO220% from the baseline)Timepoint: 5-minutes after endotracheal intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Overall rate of first attempt successful intubation (with/without physiological instability) 2. Number of intubation attempts 3. Change in regional cerebral oxygen saturation 4. Change in SpO2 and heart rate during intubation 5. Rate of desaturation or bradycardia 6. Time to desaturation and bradycardia in seconds 7. Minimum peripheral oxygen saturation 8. Minimum heart rate during intubation 9. Median duration of SpO2 less than 95% in seconds 10. Cumulative duration of desaturation and bradycardia in all intubation attempts 11. Incidence of adverse eventsTimepoint: Within 72 hours of randomization | — |
Countries
India
Contacts
Public ContactPoonam Singh
All India Institute of Medical Sciences, Rishikesh
Outcome results
None listed