Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Endotracheal intubation: After induction with Thiopentone 5mg/kg body weight IV till the loss of eyelash reflexes. 0.1 mg/kg body weight of vecuronium IV will be administered to all pat
Sponsors
JSSAHER
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients of American Society of Anaesthesiologists (ASA) Physical status Class I and II, who will be scheduled to undergo elective surgery under general endotracheal anaesthesia and fulfilled the inclusion criteria mentioned hereafter, at JSS Medical College and Hospital, Mysore.
Exclusion criteria
Exclusion criteria: Patients with a history of motion sickness. Patients who are already on treatment with anti-emetics, a steroid medication, or any other drug known to cause emesis currently or in the immediate past. Patients with known hypersensitivity to isoflurane or thiopentone. Pregnant or nursing mothers. Patients with severe hepatic, renal, or cardiac diseases. Obese patients with BMI >30kg/m2. Patients with an anticipated difficult airways. Vomiting within 24 hours before surgery or of any organic etiology.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the incidence of PONV during the first twenty-four hours (24 hours) after surgery. Severity of PONV, Number of rescue antiemetic medications required, Assessment of Apfel scoring, and comparison with the incidence and severity of PONV Timepoint: At immediate, 2, 4, 6, 12, 18, and 24 hours postoperative period. | — |
Secondary
| Measure | Time frame |
|---|---|
| The severity of PONV, Number of rescue antiemetic medications required, Assessment of Apfel scoring, and comparison with the incidence and severity of PONV Timepoint: At immediate, 2, 4, 6, 12, 18 and 24 hours post-operative period. | — |
Countries
India
Contacts
Public ContactDR GURUDATT CL
JSS MEDICAL COLLEGE AND HOSPITAL
Outcome results
None listed