Health Condition 1: E663- Overweight
Conditions
Interventions
Intervention1: 1500 kcal/day balanced diet through meal replacement shake (Optifast) and dietary advice: Optifast â?? A commercially available meal replacement shake which is composed of 38g of protei
Sponsors
Christian Medical College, Vellore
Eligibility
Inclusion criteria
Inclusion criteria: BMI more than or equal 25 kg per metre square
Exclusion criteria
Exclusion criteria: Known case of Diabetes Mellitus Any acute or chronic illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Estimation of dropout rate and the reasons for it 2. Compliance with the intervention as assessed by food diary and the factors affecting it including subjective measure of hunger and satiety 3.Change in insulinogenic index and disposition index measured during the mixed meal challenge test Timepoint: 4 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| â?¢ Change in body weight â?¢ Change in the waist and hip circumference â?¢ Change in SAT and VAT mass measured through DEXA â?¢ Change in HOMA-IR and HOMA-B measured from fasting glucose and insulin â?¢ Change in Matsuda index measured during mixed meal challenge test â?¢ Change in serum triglyceride level Timepoint: 4 weeks | — |
Countries
India
Contacts
Public ContactPadmanaban Venkatesan
Christian Medical College, Vellore
Outcome results
None listed