Comparison of pain after using different root canal sealers in single-visit root canal treatment in patients.

Effect of Different Root Canal Sealers on the Incidence and Intensity of Post-Endodontic Pain - A Randomised Clinical Controlled Trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/04/051758

Enrollment

160

Registered

2023-04-19

Start date

Unknown

Completion date

Unknown

Last updated

2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R688- Other general symptoms and signs Health Condition 2: R688- Other general symptoms and signs

Interventions

Intervention1: CeraSeal vs Apexit vs BioC sealers: Sealer is applied on Gutta Percha cone and placed in the root canal. Control Intervention1: AH PLUS sealer: the 3 types of sealers will be compared t

Eligibility

Inclusion criteria

Inclusion criteria: Mature mandibular premolar teeth with symptomatic irreversible pulpitis, sufficient tooth structure for adequate isolation, Roots with fully formed apices, No history of previous endodontic therapy

Exclusion criteria

Exclusion criteria: Immunocompromised patients, pregnant females, Analgesic intake within past 3 days, Antibiotics intake in the last month, Periodontally compromised teeth, Previously accessed teeth, Teeth not suitable for rubber dam isolation, Calcified roots lesion associated expansion of cortical bone

Design outcomes

Primary

Measure	Time frame
EVALUATION OF POST-OPERATIVE PAINTimepoint: 1 DAY, 3 DAYS	—

Secondary

Measure	Time frame
Pain ReliefTimepoint: 7 DAYS	—

Countries

India

Contacts

Public ContactMAMTA SINGLA

SGT Dental College and Hospital, Gurugram, Haryana

mamta.singla@sgtuniversity.org

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026