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To compare the effects of Umbilical Cord Milking and Delayed Cord Clamping in preterm babies

Effect of Intact Umbilical Cord Milking vs Delayed Cord Clamping on hemoglobin levels and outcomes in preterm neonates – A Randomized controlled trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/04/051733
Enrollment
238
Registered
2023-04-18
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: intact umbilical cord milking: This will consist of manual milking or stripping of the accessible length (20-25 cm) of umbilical cord from placental end to the neonate’s umbilicus 4 tim

Sponsors

Kasturba Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All preterm neonates born at the gestational age of 28weeks to 36weeks 6days

Exclusion criteria

Exclusion criteria: mothers: Monochorionic pregnancies, HIV positive mother, Maternal eclampsia, Ante partum haemorrhage neonates: Neonates requiring immediate resuscitation, including non-vigorous babies needing resuscitation, Rh iso-immunisation with hydrops, Antenatally detected congenital cardiac anomalies, Twin to twin transfusion syndrome

Design outcomes

Primary

MeasureTime frame
Hemoglobin, Hematocrit and serum Ferritin levelsTimepoint: at 6 weeks age

Secondary

MeasureTime frame
Hemoglobin and hematocrit levelsTimepoint: at 48hrs of life;Hyperbilirubinemia requiring phototherapy Timepoint: first 2 weeks of life;pRBC transfusionsTimepoint: 2 weeks of life;pRBC transfusions during hospital stay Intraventricular haemorrhage and necrotizing enterocolitis Severity of respiratory distress Mortality Timepoint: During hospital stay/until discharge

Countries

India

Contacts

Public ContactDr Shruthi K Bharadwaj

KASTURBA MEDICAL COLLEGE, MANIPAL

leslie.lewis@manipal.edu

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026