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comparison of the effects of combination of two drugs used for giving spinal anesthesia for surgeries below the umbilicus.

Comparison of the effects of the intrathecal dexmedetomidine versus clonidine as an adjuvant to hyperbaric ropivacaine 0.75% for infraumbilical surgeries: A prospective randomised study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/04/051732
Enrollment
180
Registered
2023-04-18
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: Intrathecal Ropivacaine plus Clonidine: In this group 3 ml of 0.75% hyperbaric Ropivacaine + 30 ug of clonidine in 0.5ml normal saline. Total volume 3.5ml will be given intrathe

Sponsors

Dr Shruti Desai
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I and II BMI Patients who have given written informed consent. Patients undergoing elective infraumbilical surgeries under spinal anaesthesia

Exclusion criteria

Exclusion criteria: 1.ASA grade III and IV 2.Patients with known psychiatric illness, chronic pain or any condition that precludes intrathecal anesthesia. 3.Patients with deformity of the spine. 4.Patients with skin infection at the site of anesthesia. 5.Known sensitivity or allergy to the study drugs 6.Patients on chronic anticoagulants or antit platelet drugs or patients with coagulopathy

Design outcomes

Primary

MeasureTime frame
To compare the onset and duration of sensory and motor blockade and duration of postoperative analgesiaTimepoint: The effects will be assessed at baseline,5,10,15, 20,25,30,60,90,120,150,180 minutes after giving spinal anesthesia.Postoperatively the analgesia effect will be assessed at baseline, 1,2,3,4,5,6,12 and 24 hours postoperatively.

Secondary

MeasureTime frame
to assess perioperative hemodynamic stability and incidence of side effectsTimepoint: The hemodynamic stobility and adverse effects will be assessed intraoperatively at baseline,5,10,15, 20,25,30,60,90,120,150,180 minutes after giving spinal anesthesia. And Postoperatively it will be assessed at baseline, 1,2,3,4,5,6,12 and 24 hours postoperatively.

Countries

India

Contacts

Public ContactDr Shruti Desai

GCS medical college, hospital and research centre

shru30791@gmail.com9429525791

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026