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â??Development of micronutrient rich grain based blended flours - Impact of food-to-food fortification technology and processing on micronutrient content, bio- availability, shelf life and acceptabilityâ??

â??Development of micronutrient rich grain based blended flours - Impact of food-to-food fortification technology and processing on micronutrient content, bio- availability, shelf life and acceptabilityâ??

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/04/051647
Enrollment
202
Registered
2023-04-17
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Micronutrient blended flour: Micronutrient rich grain based flour will be developed from Cereals(Wheat) and Millets(Finger millet-Ragi and Pearl millet-Bajra) The duration of the GI s

Sponsors

ICMR- National Institue of Nutrition
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Apparently healthy 20â??39 year old individuals, non-pregnant, non-lactating and willing to participate in the study. Individuals with normal BMI (19-25 kg/m2) and fasting blood glucose between 70-100 mg/dl.

Exclusion criteria

Exclusion criteria: Current illness (fever, GI disturbances, etc.,), Food intolerance/allergies, sleep disorders Taste/odour perception disorders, color blindness, denture defects, Minor infections of nose and throat, Medical history of chronic diseases and comorbidities. Medication that interferes with carbohydrate metabolism.

Design outcomes

Primary

MeasureTime frame
It will help to identify feasibility of food to food fortification of common cereal with millets. The study will generate database on calcium, iron and zinc and its bioavailability in the blended flour Information on inhibitors such as phytic acid, dietary fibre will be generated. The study will generate the acceptability of the traditional foods prepared using blended flours. To determine glycemic index and glycemic load of the blended flours based foods developed.Timepoint: Four products will be developed from the blended flour. Fasting blood glucose will be monitored at 15 mins and immediately before glucose consumption ( -15 and 0 min). 50g glucose solution will be provided to the participants and blood will be drawn at 15,30,45,60,90 and 120 mins after the first sip of the drink, the same procedure will be followed with test food. Each of the reference food, the test food will be consumed on 3 random days with a wash out period of 2 days between the foods

Secondary

MeasureTime frame
The contribution of calcium,iron and zinc from the blended flours to the EAR of women of reproductive age, children and elderly will be knownTimepoint: 3 years

Countries

India

Contacts

Public ContactDr Madhari Srisailam Radhika

ICMR- National Institute of Nutrition

radhika.madhari@gmail.com9440401160

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026