Effect often clonidine when given 90 mins prior to surgery to see effect on blood pressure and heart rate stability after we do endotracheal intubation

Comparison between two different doses of tablet clonidine(100 and 150 mcg) given 90 minutes prior to surgery to attenuate hemodynamic changes during endotracheal intubation

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/04/051634

Enrollment

Registered

2023-04-17

Start date

Unknown

Completion date

Unknown

Last updated

2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I159- Secondary hypertension, unspecified

Interventions

Intervention1: Clonidine 150mcg and 100 mcg: Comparative study between two different doses of tablet clonidine 150 mcg and 100 much to check the effect of hemodynamic stability achieved with it Interv

Eligibility

Inclusion criteria

Inclusion criteria: Patient giving informed consent

Exclusion criteria

Exclusion criteria: Lack of patient consent History of bronchial asthma, myocardial infarction

Design outcomes

Primary

Measure	Time frame
Hemodynamic stability during endotracheal intubationTimepoint: Effects of both the doses of tablet clonidine on hemodynamic stability 90 mins after the drug administration when intubation will be performed intubation and post intubation 1 min then 3 mins ,5 mins ,10 mins and after every 15 mins and so on till the end of surgery	—

Secondary

Measure	Time frame
VAS SCORE at 15 minutesTimepoint: Vas score at 15 minutes	—

Countries

India

Contacts

Public ContactDr Sheetal Gambhir

JNUIMSRC

Spsharmadr@yahoo.com9414293768

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026