Health Condition 1: K089- Disorder of teeth and supporting structures, unspecified
Conditions
Interventions
Intervention1: Platelet rich plasma: single dose of submucosal injection of prp into specific site on the root tip of the canine on the buccal and palatal sides. The injection will not be repeated aga
Sponsors
Dr DY Patil Dental College
Eligibility
Inclusion criteria
Inclusion criteria: 20 participants between the ages of 16 and 35 who have a full complement of teeth and good periodontal health and no severe medical history or metabolic bone disease will be chosen for the study. The selected subjects either had bimaxillary protrusion or Class II Division I malocclusion, undergoing orthodontic treatment and requiring extraction of 1st premolars
Exclusion criteria
Exclusion criteria: Exclusion criteria for the trial will be those with periodontal diseases/poor oral hygiene, patients with autoimmune diseases, pregnancy, and lactation and those on medication (e.g. antibiotics, antihistamines, cortisone, hormones, and any other medication that may interfere with the inflammatory process or adversely affect the periodontium) and syndromic patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| INCREASED RATE OF TTOTH MOVEMENT BY ATLEAST 1.5% THAN NORMAL DUE TO THE EFFECT OF PRPTimepoint: We intend to check the amount of tooth movement at 1, 2 and 3 months time interval | — |
Secondary
| Measure | Time frame |
|---|---|
| EFFECT OF BIOMARKERS IN THE GCF COLLECTED DURING THE 3 MONTHS OF TRIAL PERIODTimepoint: 3 MONTHS | — |
Countries
India
Contacts
Public ContactArundhati Das
Dr. D. Y. Patil Dental College and Hospital, Pune
Outcome results
None listed