Health Condition 1: H598- Other intraoperative and postprocedural complications and disorders of eye and adnexa, not elsewhere classified
Conditions
Interventions
Intervention1: Moxifloxacin 0.5%: Topical Moxifloxacin eye drop is used as a prophylactic drug in cataract surgery instead of topical ciprofloxacin eye drop.
one drop of this drug will be instilled in
Sponsors
JIPMER
Eligibility
Inclusion criteria
Inclusion criteria: All patients above 40 years of age who are enrolled for cataract surgery will be included in the study.
Exclusion criteria
Exclusion criteria: 1. Ocular or systemic infection; 2. presence of ec-tropion, entropion, trichiasis or distichiasis; 3. usage of systemic or topical antibiotics or steroids within 30 days of enrolling in the study; 4. primary or sec-ondary immunocompromised patients; 5. debilitated patients; 6. chronic renal failure patients on dialysis; 7. patients allergic to iodine or fluoroquinolone anti-biotics; 8. inability to comprehend or unwilling to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the effect of preoperative Ciprofloxacin compared to Moxifloxacin by assessing the difference in the proportion of eyes with negative bacterial cul-tureTimepoint: The first culture will be obtained before instilling the antibiotic drops (T0).Both the groups will receive antibiotic drops at 2pm, 6pm, 10pm and 8 am. An hour following the last antibiotic drop, a second conjunctival culture will be taken (T1). | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine the efficacy of ciprofloxacin and moxi-floxacin on the bacterial isolates from conjunctival cultures. To determine the clinical signs of infection in both group of patients postoperatively at one week and four weeksTimepoint: To determine the clinical signs of infection in both group of patients postoperatively at one week and four weeks | — |
Countries
India
Contacts
Public ContactDr NIRUBAN G
JIPMER, KARAIKAL
Outcome results
None listed