Herbal Mouthwash for managing radiation - induced Oral Mucositis.

Effectiveness of Natural Products based mouthwash for managing radiation - induced Oral Mucositis among Head and Neck Cancer patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/04/051471

Enrollment

Registered

2023-04-11

Start date

Unknown

Completion date

Unknown

Last updated

2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K137- Other and unspecified lesions of oral mucosa

Interventions

Intervention1: Drug - herbal mouthwash: pomegranate, honey mouthwash. Dose - 66ug/mL Frequency - 4 times a day. Route of administration - Oral Total duration of administration - 60 days. Control Inte

Eligibility

Inclusion criteria

Inclusion criteria: Patients having histologically confirmed squamous cell carcinoma of head and neck region, except that of the oral cavity, scheduled for radiotherapy, willing to sign the informed consent will be included.

Exclusion criteria

Exclusion criteria: Patients with Cancer of the oral cavity, non-healing ulcers in the oral cavity, patients using any other mouthwashes, pregnant women.

Design outcomes

Primary

Measure	Time frame
Although many clinical studies attempting to reduce radiation-induced oral mucositis have been reported, there is no widely accepted effective agent for the treatment of radiation-induced oral mucositis. With this background, the aim of the present investigation is to evaluate the efficacy of herbal mouthwash containing pomegranate whole fruit extract and honey as a prudent and cost-effective method for healing oral mucositis in head and neck cancer patients undergoing radiotherapy.Timepoint: At baseline 1st week 2nd week 3rd week 4th week 5th week 6th week in the hospital and 8th week during follow - up visit.	—

Measure

Time frame

Although many clinical studies attempting to reduce radiation-induced oral mucositis have been reported, there is no widely accepted effective agent for the treatment of radiation-induced oral mucositis. With this background, the aim of the present investigation is to evaluate the efficacy of herbal mouthwash containing pomegranate whole fruit extract and honey as a prudent and cost-effective method for healing oral mucositis in head and neck cancer patients undergoing radiotherapy.Timepoint: At baseline 1st week 2nd week 3rd week 4th week 5th week 6th week in the hospital and 8th week during follow - up visit.

—

Secondary

Measure	Time frame
not applicableTimepoint: none	—

Countries

India

Contacts

Public ContactDr SATHEESH KUMAR BHANDARY B

K. S Hegde Medical Academy

vc@nitte.edu.in9845130517

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026