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Comparing pain relief between dexmedetomidine and dexamethasone with ropivacaine after costotransverse block in patients undergoing breast surgeries.

Comparative evaluation of Dexmedetomidine versus Dexamethasone as adjuvant to ropivacaine 0.75% in ultrasound guided single shot costotransverse block for analgesia in unilateral breast surgeries: A Randomized Clinical Trial.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/04/051463
Enrollment
60
Registered
2023-04-11
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine as an adjuvant to ropivacaine: Patients randomized to this group will receive single shot costotransverse block with 0.75% ropivacaine and dexmedetomidine 1mcg/kg and wi

Sponsors

Department of Anaesthesia and Intensive care
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) class I-II Age more than 18 years at the date of inclusion Females posted for breast surgery Who have received thorough information and have signed the informed written consent form

Exclusion criteria

Exclusion criteria: Patient refusal ASA III- IV including patient with severe respiratory,cardiovascular, liver and metabolic or pre-existing neurological deficit Skin infection at puncture site Allergy to study drugs Recent history of use of analgesic/steroid drugs Pregnant patient History of psychiatric illness and substance abuse. Morbid obesity BMI >40 kg/m2 Coagulation abnormalities (INR >1.5,thrombocytopenia)

Design outcomes

Primary

MeasureTime frame
To evaluate the efficacy of dexmedetomidine versus dexamethasone as an adjuvant to ropivacaine on pain relief after costotransverse block by determining the quality of recovery assessed using Quality of Recovery(QoR-15) scale at 24 hour post operatively.Timepoint: At 24 hrs.

Secondary

MeasureTime frame
To determine the time for first requirement of analgsia. Total cumulative dose of rescue analgesic (tramadol) consumption in the 24 h after surgery. VAS scores at rest and on arm movements. Patient satisfaction with block. Future willingness to undergo repeat peripheral nerve block. Note any side effects.Timepoint: 1hr, 4hr, 8hr, 12hr, 24hr.

Countries

India

Contacts

Public ContactDr Swati

Government Medical College and Hospital, Sector 32 Chandigarh.

swatirohitjindal604@gmail.com9646004171

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026