FindTrial
Sign In

Comparing the effect of Ephedrine and Phenylephrine infusion on hemodynamic stability after Spinal Anaesthesia in elderly patients

A Comparative study of infusion of Ephedrine and Phenylephrine on hemodynamic stability after Spinal Anaesthesia in elderly patients undergoing lower limb Orthopaedic Surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/04/051451
Enrollment
174
Registered
2023-04-10
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Injection EPHEDRINE: Alpha and Beta Adrenergic agonist which increases Cardiac output and prevents decrease in Heart rate Route: Intravenous Injection Dosage: 30mg Frequency: Infusion f

Sponsors

Shri B M Patil Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age above 60 years Patients undergoing lower limb orthopaedic surgeries

Exclusion criteria

Exclusion criteria: Infection at the site of injection Uncontrolled hypovolemia Allergy or Hypersensitivity to Vasoconstrictors Increased intracranial pressure Coagulopathy,sepsis,fixed cardiac output states,neurological disease Uncontrolled Hypertension,Diabetes Mellitus and Heart failure Phaeochromocytoma Hypothyroidism MAO inhibitors,Tricyclic Antidepressants Phenothiazine compounds Recent MI and CABG

Design outcomes

Primary

MeasureTime frame
To compare the effect of Ephedrine and Phenylephrine on hemodynamic stability after spinal anaesthesiaTimepoint: 30 minutes—

Secondary

MeasureTime frame
To compare the number of rescue doses of Ephedrine and Phenylephrine given after spinal anaesthesiaTimepoint: 30 minutes—

Countries

India

Contacts

Public ContactSyed Sufian Ibrahim

Shri B M Patil Medical College

drbnp2000@gmail.com7829655342

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026