Health Condition 1: B949- Sequelae of unspecified infectiousand parasitic disease
Conditions
Interventions
None listed
Sponsors
Armed forces Medical services research project
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients with sepsis admitted to the ICU
Exclusion criteria
Exclusion criteria: a. Age b. Consent not available c. Patients on therapeutic anticoagulation d. Patients with known chronic liver disease. e. Patients with primary hematological disorders. f. Patients in whom blood and blood products have been transfused within the past 48h. g. Patients on Vitamin K supplementation. h. Patients with pre-existing hypo or hypercalcemia. i. Patients with known congenital coagulation disorders. j. Patients who underwent surgery 07 days prior to enrollment. k. Pregnancy and peripartum period (up to 8 weeks post-delivery) l. Patients presenting with a primary diagnosis of trauma. m. Patients diagnosed with sepsis for more than 72h before enrolment/ admission to ICU.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Need for blood and component transfusions.Timepoint: during the detection of any abnormal test results. | — |
Primary
| Measure | Time frame |
|---|---|
| The results of the conventional tests of coagulation and ROTEM/TEG will be interpreted as the presence or absence of abnormal coagulation. These rates will be compared using the appropriate statistical method.Timepoint: Three time phases of sepsis will be determined starting from the likely time of onset of sepsis less than 3 days 3 to7 days and more than 7 days. | — |
Countries
India
Contacts
Public ContactKRISHNA KUMAR MYLAVARAPU
Army Hospital Research and Referral
Outcome results
None listed