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Comparing two drugs Noradrenaline Vs Vasopressin for management of blood pressure in case of infection

Comparison of Noradrenaline first vs Vasopressin first in the management of Septic shock

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/04/051400
Enrollment
60
Registered
2023-04-10
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I958- Other hypotension

Interventions

Intervention1: Noradrenaline: Patients will be administered intravenous infusion of Noradrenaline starting with a dose of 0.05 micrograms/kg/min. Intravenous Vasopressin infusion will be added to this

Sponsors

Virinchi Hospitals
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: i) Patient refusal ii) Patients below 18 years of age iii) Patients already on vasopressors prior to hospital admission iv) Ongoing myocardial or bowel ischemia v) Any documented acute peripheral vascular disease

Exclusion criteria

Exclusion criteria: i) Patient refusal ii) Patients below 18 years of age iii) Patients already on vasopressors prior to hospital admission iv) Ongoing myocardial or bowel ischemia v) Any documented acute peripheral vascular disease

Design outcomes

Primary

MeasureTime frame
Time required for shock reversal in patients of each groupTimepoint: Baseline and 12th hourly lactates till his lactates are less than 2mmol/L which will be considered as shock reversal

Secondary

MeasureTime frame
i) Number of vasopressor days ii) Number of ventilator days iii) Number of renal replacement therapy days iv) Total length of ICU stay Timepoint: Patient will be monitored continuously in the ICU and number of days patient requiring ventilator support,vasopressor support,renal requirement therapy will be noted during his stay in ICU.

Countries

India

Contacts

Public ContactSrinivas Samavedam

Virinchi Hospitals

srinivas3271@gmail.com9866343632

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026