Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Hydroxy Methyl Butyrate (HMB) Group: Hydroxy Methyl Butyrate (HMB) 1.5g oral will be supplementated everyday for two weeks before the cardiac surgery.
Control Intervention1: Control gro
Sponsors
The Madras Medical Mission, Chennai
Eligibility
Inclusion criteria
Inclusion criteria: Elective Cardiac surgery using cardiopulmonary bypass Patients with adequate LV function Patients with mild to moderate LV dysfunction
Exclusion criteria
Exclusion criteria: Patients with Severe LV dysfunction Preexisting kidney disease Preexisting liver disease Smoking, drug/alcohol abuse Hepatitis B & C infection Endocrine disorders Autoimmune disorders Patients already on protein supplementation Offpump cardiac surgeries Patient refusal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome of the study is to determine whether preoperative supplementation of Beta-Hydroxy-Beta-Methyl butyrate (HMB) improves the outcome in the elective cardiac surgery on cardiopulmonary bypass (CPB).Timepoint: The patient is assessed one day before supplemenation and 2 weeks after supplementation, and again on the first post operative day | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome of the study is to determine the duration of ICU stay, mechanical ventilation, wound infections and post op complications. Timepoint: The patient is assessed one day before supplementation and 2 weeks after supplementation and again on the first post operative day. | — |
Countries
India
Contacts
Public ContactDr Rameez Raja
The Madras Medical Mission, Chennai
Outcome results
None listed