Health Condition 1: F102- Alcohol dependence Health Condition 2: F102- Alcohol dependence
Conditions
Interventions
Intervention1: Deep Transcranial Magnetic Stimulation (dTMS), Active: The helmet with H7 dTMS coil
will be placed on the head of the
patient. It will be adjusted such
that, the maximal stimulation is
Sponsors
Central Institute of Psychiatry
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with mental and behavioural disorders due to use of alcohol, dependence syndrome, currently using the substance (F10.24) as per International Classification of disease 10th (ICD-10, DCR)Diagnostic criteria for research. 2. Male gender 3. Age between 18-50 years 4. Ready to give written informed consent 5. Clinical institute withdrawal assessment for alcohol revised (CIWA-ar) score less than 10.
Exclusion criteria
Exclusion criteria: 1. Any other co-morbid substance dependence except nicotine and caffeine. 2. Participants with any co-morbid psychiatric disorder. 3. History of severe withdrawal e.g., convulsions or delirium tremens during abstinence. 4. Color-blind patients 5. Not willing to give written informed consent. 6. Patient with presence of pacemaker or other electronic implants, metal or magnetic objects in the brain.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in scores of craving as rated by Alcohol Craving Questionnaire (ACQ) and Obsessive Compulsive Drinking Scale (OCDS).Timepoint: Reduction in scores of craving as rated by Alcohol Craving Questionnaire (ACQ) and Obsessive Compulsive Drinking Scale (OCDS) as assessed at the end of 2 weeks of dTMS treatment and after 4 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in the amplitude and latency of the P300 component of ERP on Stroop task.Timepoint: Changes in the amplitude and latency of the P300 component of ERP on Stroop task will be assessed before and at end of 2 weeks of dTMS treatment | — |
Countries
India
Contacts
Public ContactDr Aniruddha Mukherjee
Central Institute of Psychiatry
Outcome results
None listed