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Head and neck cancer patients undergoing oncosurgery- assessment of perioperative stress via Role of Sleep quality and duration of preoperative fasting.

Role of Sleep quality and duration of preoperative fasting in determining perioperative stress in head and neck cancer patients undergoing elective onco-surgery in Indian population - -

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/04/051301
Enrollment
86
Registered
2023-04-05
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx

Interventions

Intervention1: sleep analysis and stress biomarkers measurement preopeatively and post operatively: sleep analysis and duration of preoperative fasting in assessing stress via stress biomarkers (serum

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients having head and neck cancer undergoing elective tumor resection surgery

Exclusion criteria

Exclusion criteria: 1.Less than 18 years age. 2. patients apart from head and neck cancers. 3. Patient with pre-existing (before diagnosis of cancer) history of sleep disturbance or hereditary sleep disturbance. 4. Patient with advance cardio-pulmonary compromise (NYHA class 4). 5. Patients with history of psychiatric illness mainly Schizophrenia or other psychosis or neurosis. 6. Patient unable to communicate or understand the assessment tools. 7. BMI more than 30. 8. Diabetic patients and Hypertensive patients. 9. Patients receiving exogenous thyroid supplements or antithyroid medications. 10. ASA grade IlI and IV. 11. Major blood loss during surgery. 12. Missing data on study variables 13. Patients refusing informed consent 14. Patients receiving medications known to interfere with hormonal response to stress (e.g. Beta blockers, steroids etc)

Design outcomes

Primary

MeasureTime frame
1. IVCCI as a determinant of intravascular volume status.(average of 3 readings) 2. Sleep score as determined by the wrist sleep tracking device (average reading of 3 preoperative days). 3. Serum cortisol and CRP levels (taken 8PM previous day, 8AM in the morning, 2 hours after induction of anaesthesia and 24 hours after surgery).Timepoint: serum stress biomarkers taken 8PM previous day, 8AM in the morning, 2 hours after surgery and 24 hours after surgery—

Secondary

MeasureTime frame
Relation between sleep score (as measured by wrist sleep tracking device) and stress markers (Cortisol). Relation between in hospital sleep score and the PSQI score (sleep quality over previous one month)Timepoint: 4 weeks—

Countries

India

Contacts

Public ContactEkta Gupta

AIIMS, Bhopal

anuj.jain.mln@gmail.com8435899317

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026