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Effect of preservative free travoprost on proximal tear drainage system using scan machine- a clinical study

Effect of preservative free travoprost on proximal lacrimal drainage system using ASOCT- a clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/04/051290
Enrollment
30
Registered
2023-04-05
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H401- Open-angle glaucoma

Interventions

Intervention1: Preservative free travoprost eye drops: Preservative free travoprost eye drops 0.004% will be instilled to the eye, one drop daily, OD for lifelong to newly diagnosed glaucoma patients.

Sponsors

Sankara eye hospital Shimoga .
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Newly diagnosed glaucoma patients started on topical preservative free travoprost monotherapy (0.004%) 2. Patients having diameter of punctum >=0.3 mm(0.3-0.5 mm) on slit lamp biomicroscopy before starting travoprost. 3. Patients having pretreatment imaging parameters of proximal lacrimal drainage system within normal range as measured by ASOCT.

Exclusion criteria

Exclusion criteria: 1. Patients diagnosed with glaucoma and started on treatment earlier. 2. History of long term ( more than 2 weeks) use of topical medications and oral medications likely to alter LDS. 3. Patient requiring adjuvant treatment to lower IOP during the study. 4 pretreatment abnormal imaging parameters of PLDS recorded by ASOCT. 5. Diseases of LDS like punctal and canalicular stenosis, atresia, agenesis, canaliculitis, nasolacrimal duct Obstruction NLDO, tumours/ lesions involving the LDS. 6. Eyelid malpositions like ectropion, entropion. 7. Cicatrising ocular diseases likely to affect LDS like Steven Johnson Syndrome, Ocular cicatricial pemphigoid, chronic conjunctivitis etc. 8. Any previous history of surgeries on LDS, eyelid. 9. History of ocular trauma involving the eyelids, LDS. 10. Previous history of ocular radiotherapy for various causes.

Design outcomes

Primary

MeasureTime frame
To study the effect of preservative free travoprost on proximal lacrimal drainage system in newly diagnosed glaucoma patients using ASOCT.Timepoint: At presentation (baseline), and on follow up visit at 3rd, 6th, 9th and 12th month.—

Secondary

MeasureTime frame
Measurement of external punctal diameter, internal punctal diameter and vertical canalicular depth on ASOCT..Timepoint: At presentation (baseline), and on follow up visit at 3rd, 6th, 9th and 12th month.—

Countries

India

Contacts

Public ContactDr Poorva Dige

Sankara eye hospital, Shimoga.

maheshbhat@sankaraeye.com9480362191

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026