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In patients undergoing brain tumour surgery , retina thickness is assessed for comparison of vision before and after surgery

To study the significance of Retinal nerve fibre layer(RNFL) thickness and Ganglion cell layer thickness(GCLT) in visual prognosis in Pituitary adenoma patients undergoing surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/04/051238
Enrollment
50
Registered
2023-04-03
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D330- Benign neoplasm of brain, supratentorial

Interventions

None listed

Sponsors

Dr Arla Sai Varsha
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: - Age more than 18 years, both males and females - All cases of Pituitary macroadenoma presenting with visual complaints - Patients undergoing both transnasal and transcranial surgeries - Patients whose tumour was totally removed or whose optic apparatus was adequately decompressed

Exclusion criteria

Exclusion criteria: - Age less than 18 years - Patients unwilling to participate in the study - Patients with a history of intraocular surgery or laser surgery - Patients who had a residual tumour on postoperative CT scans were excluded from the study - Other tumours causing compression of the chiasm or optic neuropathy (including glaucoma) were excluded from the study

Design outcomes

Primary

MeasureTime frame
Mean values of pre-operative visual acuity, along with RNFL and GCLT thickness using OCTTimepoint: Time point 1: time of diagnosis

Secondary

MeasureTime frame
Post operative visual field improvement with change in thickness of RNFL & GCLTimepoint: 6 months from the date of surgery

Countries

India

Contacts

Public ContactDr ARLA SAI VARSHA

KASTURBA MEDICAL COLLEGE

girish.menon@manipal.edu7760563666

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026