To study the advantage of diluting Propofol in decreasing pain on injection in comparision to undiluted Propofol.

TO STUDY THE EFFECT OF DILUTION ON PROPOFOL INDUCED INJECTION PAIN, INDUCTION TIME AND POSTOPERATIVE PHLEBITIS AT INJECTION SITE: A RANDOMIZED CONTROLLED STUDY

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/03/051218

Enrollment

130

Registered

2023-03-31

Start date

Unknown

Completion date

Unknown

Last updated

2023-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dilution of Propofol: To compare the effect of undiluted 1% propofol emulsion with 0.5% propofol (diluted with normal saline) on pain at injection site, induction time assessed by loss

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients of either sex 2) Age 18 to 60 years 3) American society of anaesthesiologists (ASA) physical status I& II

Exclusion criteria

Exclusion criteria: 1) Patient refusal 2) ASA Physical status III & IV 3) Pregnant women 4) Intellectually challenged patients 5) Patients with a known history of allergy to propofol or its components

Design outcomes

Primary

Measure	Time frame
Pain during propofol injection at injection site.Timepoint: At the time of injecting propofol.	—

Secondary

Measure	Time frame
To compare time to induction by loss of verbal response, bispectral index and Postoperative phlebitisTimepoint: 2 years	—

Countries

India

Contacts

Public ContactDr RAYINI PRAMOD

ESIC Medical college hosp

gopi59@hotmail.com9848024306

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026